Editions universitaires europeennes ( 05.03.2019 )
€ 39,90
The important role of vitamins is well known with regard to human health and disease. In this book, we review the effects of vitamins, A, B and C on the structure and dynamics of DNA and RNA. The conjugations of vitamin A (retinol and retinoic acid), vitamin B (folic acid) and vitamin C (L-ascorbic acid) by DNA and tRNA were analyzed. The loading efficacies of these vitamins with DNA and RNA were compared in solution. Vitamins bind nucleic acids via hydrophilic, hydrophobic and H-bonding contacts with vitamin C forming more stable DNA and tRNA adducts. The loading efficacies of these vitamins were from 40% to 60%. Vitamins induce major DNA and RNA structural changes, while biopolymers remain in native conformations.
Détails du livre: |
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ISBN-13: |
978-613-1-55437-7 |
ISBN-10: |
6131554374 |
EAN: |
9786131554377 |
Langue du Livre: |
English |
de (auteur) : |
Heidar-Ali Tajmir-Riahi |
Nombre de pages: |
88 |
Publié le: |
05.03.2019 |
Catégorie: |
Biochimie, Biophysique |